Anti-MORF4L1 Polyclonal AntibodyAnt-上海极威生物商城-Elisa试剂盒,白介素ELISA试剂盒,酶联免疫试剂盒,Gibco胎牛血清,Hyclone胎牛血清,胎牛血清等实验耗材一站式采购平台

产品简介

英文名称	Anti-MORF4L1 Polyclonal Antibody
靶标	MORF4L1
别名	MORF4L1;Eaf3;FWP006;HsT17725;MEAF3;MORFRG15;MRG15;S863-6;mortality factor 4 like 1
宿主	Rabbit
预测交叉反应	Gorilla
稀释比例	WB 1:1000-3000.
Gene ID	10933
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q9UBU8
蛋白分子量	27/37/41kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Nucleus
免疫原	Recombinant protein of human MORF4L1
亚型	IgG
纯化方法	Affinity purification
背景资料	Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction； tumor suppressor mediated growth arrest and replicative senescence； apoptosis； and DNA repair. The NuA4 complex ATPase and helicase activities seem to be； at least in part； contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2； BRCA2 and RAD51； but not BRCA1； to DNA-damage foci.
Public Immunogen Range	1-324aa
克隆类型	Polyclonal Antibody
交叉反应	Human;Mouse;Rat
应用	WB
规格	50ul100ul