Anti-PARP Polyclonal AntibodyAnti-P-上海极威生物商城-Elisa试剂盒,白介素ELISA试剂盒,酶联免疫试剂盒,Gibco胎牛血清,Hyclone胎牛血清,胎牛血清等实验耗材一站式采购平台

产品简介

英文名称	Anti-PARP Polyclonal Antibody
别名	ADP ribosyltransferase (NAD+;poly (ADP ribose) polymerase);ADP ribosyltransferase NAD+;ADPRT 1;ADPRT;ADPRT1;msPARP;NAD(+) ADP ribosyltransferase 1;pADPRT 1;pADPRT1;PARP 1;PARP1;Poly (ADP ribose) polymerase 1;poly (ADP ribose) polymerase family, member 1;Poly adenosine diphosphate ADP ribose polymerase;Poly ADP ribose polymerase 1;Poly ADP ribose polymerase family member 1;Poly ADP ribose synthetase 1;poly(ADP ribose) synthetase;poly(ADP ribosyl)transferase;Poly[ADP ribose] synthetase 1;PPOL;sPARP 1;sPARP1
宿主	Rabbit
稀释比例	WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. Flow-Cyt 0.2μg/Test. IF 1:100-500.
Gene ID	142
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P09874
蛋白分子量	116kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm Nucleus matrix Nucleus membrane Peripheral membrane protein
免疫原	KLH conjugated synthetic peptide derived from human PARP
亚型	IgG
纯化方法	Affinity purification
背景资料	Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR. Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. With EEF1A1 and TXK, forms a complex that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
克隆类型	Polyclonal Antibody
交叉反应	HumanCowDogRatMouse
应用	WBIFFlow-CytIHC-FIHC-PELISA
规格	50ul100ul