Cat. Number：GV-12106R-FITC Quantity size：100ul
Concentration：1mg/ml    Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50%
Glycerol.

Background：The P2X receptor family is comprised of ligand-gated ion channels that allow  for the increased permeability of calcium into the cell in response to extracellular ATP.  The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both.  They are characterized by intracellular amino- and carboxy-termini. P2X receptors are  expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions  between neurons and to other tissues via the binding of extracellular ATP, which acts as  a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis  after prolonged exposure to high concentrations of extracellular ATP.

Also known as：ATP receptor; P2X purinoceptor 7; P2X7; P2Z receptor; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel 7; P2RX7_HUMAN.

Specificity： ●Rabbit  Polyclonal  IgG,  affinity purified by Protein A.
●Reacts with： Human,  Mouse,  Rat,  Dog,  Pig,  Horse,  Rabbit,  .
●Immunogen：  KLH conjugated synthetic peptide derived from human P2RX7
(115-160aa).
●Predicted Molecular Weight：  69kDa.

Storage：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.  Store at -20 ° C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20 °C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application： ICC=1：50-200    IF=1：50-200
Excitation spectrum： 495nm Emission spectrum： 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note：  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.